Visibly younger skin — in 12 weeks.
Skin Protocol.
Visible improvements in 6–12 weeks
The Rx skincare protocol Hims can't prescribe. A compounded night treatment, a peptide support serum, and daily photoprotection — engineered to work as one system. This is where your longevity stack begins.
Three steps.
One system.
PM Protocol
Compounded Rx night treatment. The workhorse — drives visible aging reversal.
Learn more →AM Protocol
Peptide serum. Supports collagen, softens PM Protocol irritation.
Learn more →SPF Protocol
Essential with PM Protocol. Tretinoin makes skin sun-sensitive — SPF protects what the Rx layer builds.
Learn more →Drag to see 12 weeks on protocol.
Based on median clinical response. Individual results vary.
Answered.
Can I order just one component?
Yes — each is available solo. But the three compound: PM drives change, AM keeps it tolerable, SPF preserves the outcome. Removing any one reduces the others' effectiveness.
Do I need all three to start?
PM + SPF is the non-negotiable baseline. Tretinoin without daily SPF accelerates damage instead of reversing it. AM is strongly recommended but can be added later.
How long until I see results?
Most users see smoother texture and tone within 8–12 weeks. Meaningful change in fine lines and photoaging compounds over 6–12 months of consistent use.
What if my skin reacts badly?
Message your clinician. Strength can be adjusted — your clinician can step tretinoin down to a gentler dose within 24 hours. We don't let irritation cause you to quit.
Why drugstore skincare
cannot do this.
It's not branding. It's the law. The actives that actually reverse aging require a prescription — and that's exactly what's inside Skin Protocol.
- Retinol capped at 0.025% (cosmetic-grade)
- Cannot legally claim to reverse aging
- "Peptides" that degrade in jars within weeks
- 10+ separate products to layer
- No clinician oversight
- Marginal results, marketed as miracles
- Tretinoin 0.025% — 10× stronger than retinol
- Clinically proven to reverse photoaging
- Pharmaceutical-grade actives, fresh-compounded
- Four actives in one nightly bottle
- US-licensed clinician reviews + adjusts
- Built to actually work — and to actually use
Pharmaceutical compound · 503A pharmacy · Clinician-prescribed
Same Rx.
1/3 the cost.
- 6–12 week wait for appointment
- One 15-minute consult
- Rx handed off to pharmacy
- You figure out routine alone
- $180/mo for 3 separate products
- No prescription compounds
- Retinol ≈ 20× weaker than Rx tretinoin
- No clinical oversight
- 10+ products to manage
- Marginal results at best
- Approved in 24–48 hrs online
- US-licensed clinician, full review
- Compound shipped from US pharmacy
- AM/PM protocol, built to execute
- Message your clinician anytime
Toggle on the foundation.
Start your intake.
Two minutes. Clinician reviews in 24 hours. You pay nothing until approved.
Designed to live
on your shelf.
Not in a drawer. Not at the back of the cabinet. Three minimal bottles you actually want to look at — engineered to survive humidity, travel, and the morning rush.
The clinical data.
We read the studies so you don't have to. Here's the evidence behind Skin Protocol.
Selected peer-reviewed references. Full bibliography available in your patient portal.